Hemin
Cat. No.：YN270383
| 产品名称: | Hemin |
| CAS No.: | 16009-13-5 |
| Chemical Name: | (SP-5-13)-chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,8-dipropanoato(4-)-κN21, κN22, κN23, κN24]-ferrate(2-), dihydrogen |
| Synonyms: | 氯化血红素; |
| 分子量: | 651.94 |
| 分子式: | C₃₄H₃₂ClFeN₄O₄ |
| SMILES: | [Cl-][Fe+3]123[N-]4C5=C(CCC([O-])=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC([O-])=O)=[N]3C8=C5.[H+].[H+] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hemin 是含铁的卟啉化合物。Hemin 是血红素加氧酶(HO)-1诱导剂。 |
| IC50和靶点: | |
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Taraha, S.M., Traugh, J.A., Sharp, S.B., et al.Effect of hemin on site-specific phosphorylation of eukaryotic initiation factor 2Proc. Natl. Acad. Sci. USA75(2),789-793(1978)
Vesely, M.J.J., Exon, D.J., Clark, J.E., et al.Heme oxygenase-1 induction in skeletal muscle cells: hemin and sodium nitroprusside are regulators in vitroAm. J. Physiol.275(4 Pt 1),C1087-1094(1998)
Lindenblatt, N., Bordel, R., Schareck, W., et al.Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivoArterioscler. Thromb. Vasc. Biol.24(3),601-606(2004)
Botros, F.T., Prieto-Carrasquero, M.C., Martin, V.L., et al.Heme oxygenase induction attenuates afferent arteriolar autoregulatory responsesAm. J. Physiol. Renal Physiol.295(4),F904-F911(2008)
Labbé, R.F., Finch, C.A., Smith, N.J., et al.Erythrocyte protoporphyrin/heme ratio in the assessment of iron statusClin. Chem.25(1),87-92(1979)
Bissell, D.M., and Wang, B.Acute hepatic porphyriaJ. Clin. Transl. Hepatol.3(1),17-26(2015)
