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Lumichrome

Cat. No.:YN270634

  • CAS No. :1086-80-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Lumichrome
      CAS No.: 1086-80-2
      Chemical Name: 7,8-dimethyl-benzo[g]pteridine-2,4(1H,3H)-dione
      Synonyms:光色素
      分子量:242.2
      分子式:C12H10N4O2
      SMILES:CC1=C(C)C=C(NC(C2=N3)=NC(NC2=O)=O)C3=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Lumichrome 是核黄素的光降解产物,是人体内的一种内源性化合物。Lumichrome 通过p53 依赖机制抑制人肺癌细胞生长并诱导凋亡 (apoptosis)。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Ahmad, I., Anwar, Z., Ahmed, S., et al.Solvent effect on the photolysis of riboflavinAAPS PharmSciTech.16(5),1122-1128(2015)

      Dakora, F.D., Matiru, V.N., and Kanu, A.S.Rhizosphere ecology of lumichrome and riboflavin, two bacterial signal molecules eliciting developmental changes in plantsFront. Plant Sci.6(700),(2015)

      Yamamoto, K., and Asano, Y.Efficient production of lumichrome by Microbacterium sp. strain TPU 3598Appl. Environ. Microbiol.81(21),7360-7367(2015)

      Matiru, V.N., and Dakora, F.D.The rhizosphere signal molecule lumichrome alters seedling development in both legumes and cerealsNew Phytol.166(2),439-444(2005)

      Rajamani, S., Bauer, W.D., Robinson, J.B., et al.The vitamin riboflavin and its derivative lumichrome activate the LasR bacterial quorum sensing receptorMol. Plant Microbe. Interact.21(9),1184-1192(2008)

      Tsukamoto, S., Kato, H., Hirota, H., et al.Lumichrome. A larval metamorphosis-inducing substance in the ascidian Hhalocynthia roretziEur. J. Biochem.264(3),785-789(1999)

      Balcazar, D.E., Vanrell, M.C., Romano, P.S., et al.The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protistsPLoS Negl. Trop. Dis.11(4),e0005513(2017)

      Said, H.M., Wang, S., and Ma, T.Y.Mechanism of riboflavin uptake by cultured human retinal pigment epithelial ARPE-19 cells: Possible regulation by an intracellular Ca2+-calmodulin-mediated pathwayJ. Physiol.556 (Pt 2),369-377(2005)

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