BPKDi
Cat. No.：YN270643
| 产品名称: | BPKDi |
| CAS No.: | 1201673-28-0 |
| Chemical Name: | 2′-(cyclohexylamino)-6-(1-piperazinyl)-[2,4′-bipyridine]-4-carboxamide |
| Synonyms: | |
| 分子量: | 380.48686 |
| 分子式: | C21H28N6O |
| SMILES: | O=C(C1=CC(N2CCNCC2)=NC(C3=CC=NC(NC4CCCCC4)=C3)=C1)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BPKDi 是一种有效的联吡啶PKD抑制剂，对 PKD1、PKD2 和PKD3的IC50分别为 1 nM、9 nM 和 1 nM。BPKDi 阻断心肌细胞中 IIa 类HDAC的信号依赖性磷酸化和核输出。 |
| IC50和靶点: | [{name:"PKD1:1 nM (IC50)"},{name: "PKD2:9 nM (IC50)"},{name: "PKD3:1 nM (IC50)"}] |
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| Solvent & Solubility: |
Monovich, L., Vega, R.B., Meredith, E., et al.A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinaseFEBS Lett.584(3),631-637(2010)
