4'-Bromo-resveratrol
Cat. No.：YN270647
CAS No. ：1224713-90-9
| 产品名称: | 4'-Bromo-resveratrol |
| CAS No.: | 1224713-90-9 |
| Chemical Name: | 5-[(1E)-2-(4-bromophenyl)ethenyl]-1,3-benzenediol |
| Synonyms: | 4′‐BR |
| 分子量: | 291.1 |
| 分子式: | C14H11BrO2 |
| SMILES: | OC1=CC(O)=CC(/C=C/C2=CC=C(Br)C=C2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4'-Bromo-resveratrol 是一种有效的双重抑制剂Sirtuin-1和Sirtuin-3。4'-Bromo-resveratrol 通过线粒体代谢重编程抑制黑色素瘤细胞的生长。4'-Bromo-resveratrol 通过代谢重编程和影响细胞周期和细胞凋亡信号传导在黑色素瘤细胞中发挥抗增殖作用。 |
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Nguyen, G.T.T., Gertz, M., and Steegborn, C.Crystal structures of Sirt3 complexes with 4'-bromo-resveratrol reveal binding sites and inhibition mechanismChem. Biol.20(11),1375-1385(2013)
