WEHI-539
Cat. No.：YN270665
| 产品名称: | WEHI-539 |
| CAS No.: | 1431866-33-9 |
| Chemical Name: | 5-[3-[4-(aminomethyl)phenoxy]propyl]-2-[8-[2-(2-benzothiazolyl)hydrazinylidene]-5,6,7,8-tetrahydro-2-naphthalenyl]-4-thiazolecarboxylic acid |
| Synonyms: | WEHI-539;5-[3-[4-(aminomethyl)phenoxy]propyl]-2-[(8E)-8-(1,3-benzothiazol-2-ylhydrazinylidene)-6,7-dihydro-5H-naphthalen-2-yl]-1,3-thiazole-4-carboxylic acid;WEHI 539;5-(3-(4-(Aminomethyl)phenoxy)propyl)-2-(8-(2-(benzo[d]thiazol-2-yl)hydrazono)-5,6,7,8-te |
| 分子量: | 583.7 |
| 分子式: | C31H29N5O3S2 |
| SMILES: | [H]N(/N=C1C(C=C(C2=NC(C(O)=O)=C(CCCOC3=CC=C(CN)C=C3)S2)C=C4)=C4CCC/1)C5=NC6=CC=CC=C6S5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | WEHI-539 是一种选择性的Bcl-XL抑制剂，IC50为 1.1 nM。 |
| IC50和靶点: | [{name:"Bcl-xL:1.1 nM (IC50)"}] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Lessene, G., Czabotar, P.E., Sleebs, B.E., et al.Structure-guided design of a selective BCL-XL inhibitorACS Med. Chem. Lett.5(6),662-667(2014)
