S55746 hydrochloride
Cat. No.:YN270667
CAS No. :1448525-91-4
产品名称: | S55746 hydrochloride |
CAS No.: | 1448525-91-4 |
Chemical Name: | |
Synonyms: | BCL201 hydrochloride |
分子量: | 747.28 |
分子式: | C43H43ClN4O6 |
SMILES: | O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[C@H]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | S55746 hydrochloride (BCL201 hydrochloride) 是一种有效、可口服、选择性的BCL-2抑制剂,其Ki值和Kd值分别为 1.3 nM 和 3.9 nM。S55746 hydrochloride (BCL201 hydrochloride) 具有抗肿瘤活性且毒性低。 |
IC50和靶点: | [{name:"Bcl-2:1.3 nM (Ki)"},{name: "Bcl-xL:520 nM (Ki)"},{name: "Bcl-2:3.9 nM (Kd)"},{name: "Bcl-xL:186 nM (Kd)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |