L-Glutamine-
Cat. No.:YN270668
CAS No. :1467047-25-1
产品名称: | L-Glutamine- |
CAS No.: | 1467047-25-1 |
Chemical Name: | 4-(cyclohexylamino)-3-[(phenylmethyl)amino]-benzoic acid, ethyl ester |
Synonyms: | AA9 |
分子量: | 352.47 |
分子式: | C22H28N2O2 |
SMILES: | O=C(OCC)C(C=C1NCC2=CC=CC=C2)=CC=C1NC3CCCCC3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SRS11-92 是一种 Ferrostatin-1 (Fer-1) 类似物,是一种有效的铁死亡 (ferroptosis) 抑制剂。SRS11-92 抑制 Erastin 诱导的 HT-1080 人纤维肉瘤细胞铁致细胞死亡 (EC50=6 nM)。 |
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Skouta, R., Dixon, S.J., Wang, J., et al.Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease modelsJ. Am. Chem. Soc.136(12),4551-4556(2014)
Iniguez, E.A., Perez, A., Maldonado, R.A., et al.Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania majorBioorg. Med. Chem. Lett.25(22),5315-5320(2015)