Lapatinib ditosylate
Cat. No.:YN270683
CAS No. :1793052-96-6
产品名称: | Lapatinib ditosylate |
CAS No.: | 1793052-96-6 |
Chemical Name: | 3-[(Z)-(5-pyrimidinylmethylene)amino]-4-(tricyclo[3.3.1.13,7]dec-1-ylamino)-benzoic acid, 1,1-dimethylethyl ester |
Synonyms: | tert-butyl 4-(1-adamantylamino)-3-(pyrimidin-5-ylmethylideneamino)benzoate;3-[(Z)-(5-Pyrimidinylmethylene)amino]-4-(tricyclo[3.3.1.13,7]dec-1-ylamino)-benzoic acid, 1,1-dimeth |
分子量: | 432.55804 |
分子式: | C26H32N4O2 |
SMILES: | O=C(OC(C)(C)C)C1=CC=C(NC23C[C@H]4C[C@H](C[C@H](C4)C3)C2)C(/N=C\C5=CN=CN=C5)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SRS16-86 是ferroptosis的有效抑制剂。SRS16-86 在体内比 Ferrostatin-1 对代谢和血浆更稳定。SRS16-86 可用于肾缺血再灌注损伤 (IRI) 和脊髓损伤 (SCI) 研究。 |
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Linkermann, A., Skouta, R., Himmerkus, N., et al.Synchronized renal tubular cell death involves ferroptosisProc. Natl. Acad. Sci. USA111(47),16836-16841(2014)
Zhang, Y., Sun, C., Zhao, C., et al.Ferroptosis inhibitor SRS 16-86 attenuates ferroptosis and promotes functional recovery in contusion spinal cord injuryBrain Res.1706,48-57(2019)