BI-0252
Cat. No.：YN270686
| 产品名称: | BI-0252 |
| CAS No.: | 1818291-27-8 |
| Chemical Name: | |
| Synonyms: | BI 0252;BI0252 |
| 分子量: | 566.45 |
| 分子式: | C30H26Cl2FN3O3 |
| SMILES: | C(O)(=O)C1=CC=C([C@H]2N[C@@]([H])3[C@@H](C4=CC=CC(Cl)=C4F)[C@](N(CC4CC4)[C@]3([H])C2)2C3=C(NC2=O)C=C(Cl)C=C3)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BI-0252 是一种具有口服活性，选择性的MDM2-p53抑制剂，IC50值为 4 nM。 BI-0252 可诱导异种移植小鼠 SJSA-1 的所有动物肿瘤消退，同时诱导肿瘤蛋白p53 (TP53) 靶基因和凋亡标志物。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
