LYN-1604
Cat. No.：YN270694
| 产品名称: | LYN-1604 |
| CAS No.: | 2088939-99-3 |
| Chemical Name: | 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-ethanone |
| Synonyms: | 1-{4-[2-(2,4-Dichloro-phenyl)-2-(naphthalen-2-ylmethoxy)-ethyl]-piperazin-1-yl}-2-diisobutylamino-ethanone;BCP28888;LYN 1604;BDBM50271371;1-(4-(2-(2,4-dichlorophenyl)-2-(naphthalen-2-ylmethoxy)ethyl)piperazin-1-yl)-2-(diisobutylamino)ethan-1-one;1-(4-(2-( |
| 分子量: | 584.6 |
| 分子式: | C33H43Cl2N3O2 |
| SMILES: | O=C(CN(CC(C)C)CC(C)C)N(CC1)CCN1CC(C2=CC=C(Cl)C=C2Cl)OCC3=CC4=CC=CC=C4C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LYN-1604 是一种有效的 UNC-51 样激酶 1 (ULK1) 激活剂，EC50值为 18.94 nM。LYN-1604 可用于三阴性乳腺癌 (TNBC) 的研究。 |
| IC50和靶点: | [{name:"ULK1:18.94 nM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Zhang, L., Fu, L., Zhang, S., et al.Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivoChem. Sci.8(4),2687-2701(2017)
