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C16-Ceramide

Cat. No.:YN270721

  • CAS No. :24696-26-2

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    • 生物活性
    • 参考文献
    • 产品名称: C16-Ceramide
      CAS No.: 24696-26-2
      Chemical Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexadecanamide
      Synonyms:
      分子量:537.9
      分子式:C34H67NO3
      SMILES:CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCCCC)=O)CO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: C16-Ceramide 是一种天然小分子,通过直接选择性结合激活p53。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Siskind, L.J., Kolesnick, R.N., and Colombini, M.Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrationsMitochondrion6(3),118-125(2006)

      Seumois, G., Fillet, M., Gillet, L., et al.De novo C16- and C24-ceramide generation contributes to spontaneous neutrophil apoptosisJ. Leukoc. Biol.81(6),1477-1486(2007)

      Brodlie, M., McKean, M.C., Johnson, G.E., et al.Ceramide is increased in the lower airway epithelium of people with advanced cystic fibrosis lung diseaseAm. J. Respir. Crit. Care Med.182(3),369-375(2010)

      Anroedh, S., Hilvo, M., Akkerhuis, K.M., et al.Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patientsJ. Lipid Res.59(9),1729-1737(2018)

      Schiffmann, S., Sandner, J., Birod, K., et al.Ceramide synthases and ceramide levels are increased in breast cancer tissueCarcinogenesis30(5),745-752(2009)

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