C16-Ceramide
Cat. No.:YN270721
CAS No. :24696-26-2
产品名称: | C16-Ceramide |
CAS No.: | 24696-26-2 |
Chemical Name: | N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexadecanamide |
Synonyms: | |
分子量: | 537.9 |
分子式: | C34H67NO3 |
SMILES: | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCCCC)=O)CO |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | C16-Ceramide 是一种天然小分子,通过直接选择性结合激活p53。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Siskind, L.J., Kolesnick, R.N., and Colombini, M.Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrationsMitochondrion6(3),118-125(2006)
Seumois, G., Fillet, M., Gillet, L., et al.De novo C16- and C24-ceramide generation contributes to spontaneous neutrophil apoptosisJ. Leukoc. Biol.81(6),1477-1486(2007)
Brodlie, M., McKean, M.C., Johnson, G.E., et al.Ceramide is increased in the lower airway epithelium of people with advanced cystic fibrosis lung diseaseAm. J. Respir. Crit. Care Med.182(3),369-375(2010)
Anroedh, S., Hilvo, M., Akkerhuis, K.M., et al.Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patientsJ. Lipid Res.59(9),1729-1737(2018)
Schiffmann, S., Sandner, J., Birod, K., et al.Ceramide synthases and ceramide levels are increased in breast cancer tissueCarcinogenesis30(5),745-752(2009)