Apostatin-1
Cat. No.：YN270725
CAS No. ：2559703-06-7
| 产品名称: | Apostatin-1 |
| CAS No.: | 2559703-06-7 |
| Chemical Name: | |
| Synonyms: | Apt-1 |
| 分子量: | 345.5 |
| 分子式: | C19H27N3Os |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Apostatin-1 (Apt-1) 是一种有效的TRADD抑制剂。Apostatin-1 可与TRADD-N结合 (KD=2.17 μM)，破坏其与 TRADD-C 和 TRAF2 的结合。Apostatin-1 调节RIPK1和beclin 1的泛素化。Apostatin-1 通过激活突变 tau、α-synuclein 或huntingtin积累的细胞中的自噬 (autophagy)，阻断凋亡 (apoptosis)，并恢复细胞内稳态。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
