Necrostatin-34
Cat. No.：YN270746
CAS No. ：375835-43-1
| 产品名称: | Necrostatin-34 |
| CAS No.: | 375835-43-1 |
| Chemical Name: | 2-[[3-cyano-1,4,5,6-tetrahydro-4-(4-methylphenyl)-6-oxo-2-pyridinyl]thio]-N-2-thiazolyl-acetamide |
| Synonyms: | |
| 分子量: | 384.4774 |
| 分子式: | C18H16N4O2S2 |
| SMILES: | N#CC1=C(NC(CC1C2=CC=C(C)C=C2)=O)SCC(NC3=NC=CS3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Necrostatin-34 (Nec-34) 是RIPK1激酶的抑制剂，通过占据激酶结构域的特定结合口袋，将RIPK1稳定在一个非激活的状态。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Meng, H., Wu, G., Zhao, X., et al.Discovery of a cooperative mode of inhibiting RIPK1 kinaseCell Discov.7(1),41(2021)
