7,3',4'-Trihydroxyisoflavone
Cat. No.：YN270758
| 产品名称: | 7,3',4'-Trihydroxyisoflavone |
| CAS No.: | 485-63-2 |
| Chemical Name: | 3-(3,4-dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one |
| Synonyms: | Orita13 |
| 分子量: | 270.2 |
| 分子式: | C15H10O5 |
| SMILES: | OC1=CC=C(C(C(C2=CC(O)=C(O)C=C2)=CO3)=O)C3=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 7,3',4'-Trihydroxyisoflavone 是黄豆苷元的主要代谢物，是Cot (Tpl2/MAP3K8)和MKK4的 ATP 竞争性抑制剂。7,3',4'-Trihydroxyisoflavone 具有抗癌、抗血管生成、化学保护和自由基清除活性。 |
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Park, J.-S., Kim, D.H., Lee, J.K., et al.Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitorsBioorg. Med. Chem. Lett.20(3),1162-1164(2010)
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Lee, D.E., Lee, K.Q., Song, N.R., et al.7,3',4'-Trihydroxyisoflavone inhibits epidermal growth factor-induced proliferation and transformation of JB6 P+ mouse epidermal cells by suppressing cyclin-dependent kinases and phosphatidylinositol 3-kinaseJ. Biol. Chem.285(28),21458-21466(2010)
