Cystamine (dihydrochloride）
Cat. No.：YN270764
| 产品名称: | Cystamine (dihydrochloride） |
| CAS No.: | 56-17-7 |
| Chemical Name: | 2,2'-dithiobis-ethanamine, dihydrochloride |
| Synonyms: | Decarboxycystine dihydrochloride, 2-Aminoethyl disulfide dihydrochloride, 2,2'-Dithiobisethanamine dihydrochloride |
| 分子量: | 225.2 |
| 分子式: | C4H12N2S2 • 2HCl |
| SMILES: | NCCSSCCN.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cystamine (dihydrochloride) 是游离硫醇半胱胺的二硫化物形式。Cystamine 是一种转谷氨酰胺酶 (Tgase) 抑制剂，具有口服活性。Cystamine 对 caspase-3 也有抑制活性，IC50值为 23.6 μM。Cystamine 可用于亨廷顿舞蹈病（HD）等多种疾病的研究。 |
| IC50和靶点: | [{name:"Caspase 3:23.6 μM (IC50)"}] |
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Elli, L., Ciulla, M.M., Busca, G., et al.Beneficial effects of treatment with transglutaminase inhibitor cystamine on the severity of inflammation in a rat model of inflammatory bowel diseaseLab. Invest.91(3),452-461(2011)
