L-Glutathione reduced-
Cat. No.：YN270772
CAS No. ：68341-09-3
| 产品名称: | L-Glutathione reduced- |
| CAS No.: | 68341-09-3 |
| Chemical Name: | (SP-4-2)-[[2,2'-(1,2-dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato-κN2,κS]](2-)]-copper |
| Synonyms: | |
| 分子量: | 321.9 |
| 分子式: | C8H14CuN6S2 |
| SMILES: | CC1=[N]2[Cu]([S]C(NC)=N3)([S]C(NC)=N2)[N]3=C1C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CuATSM 是一种高效的自由基捕获抗氧化剂（RTA）和（磷脂）脂质过氧化抑制剂，因此它具有抑制ferroptosis的能力。 |
| IC50和靶点: | |
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Southon, A., Szostak, K., Acevedo, K.M., et al.Cu II (atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative diseaseBr. J. Pharmacol.177(3),656-667(2020)
Roberts, B.R., Lim, N.K.H., McAllum, E.J., et al.Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosisJ. Neurosci.34(23),8021-8031(2014)
Vavere, A.L., and Lewis, J.S.Cu-ATSM: A radiopharmaceutical for the PET imaging of hypoxiaDalton Trans.43,4893-4902(2007)
