IM-54
Cat. No.:YN270781
产品名称: | IM-54 |
CAS No.: | 861891-50-1 |
Chemical Name: | 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione |
Synonyms: | |
分子量: | 325.4 |
分子式: | C19H23N3O2 |
SMILES: | CCCCCNC1=C(C(=O)N(C)C1=O)c1cn(C)c2ccccc12 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | IM-54 是一种选择性的氧化应激诱导的坏死 (necrosis) 抑制剂。IM-54 对 H2O2诱导的坏死有强烈的抑制作用。IM-54 是一种潜在的心脏保护剂和研究细胞死亡分子机制的生物工具。 |
IC50和靶点: | |
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Dodo, K., Katoh, M., Shimizu, T., et al.Inhibition of hydrogen peroxide-induced necrotic cell death with 3-amino-2-indolylmaleimide derivativesBioorg. Med. Chem. Lett.15(12),3114-3118(2005)