FINO2
Cat. No.：YN270784
| 产品名称: | FINO2 |
| CAS No.: | 869298-31-7 |
| Chemical Name: | (5α,8α)-8-(1,1-dimethylethyl)-3-methyl-1,2-dioxaspiro[4.5]decane-3-ethanol |
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| 分子量: | 256.38102 |
| 分子式: | C15H28O3 |
| SMILES: | CC(C)(C)[C@@H](CC1)CC[C@]21CC(CCO)(C)OO2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | INO2 是一种有效的ferroptosis诱导剂。FINO2 抑制 GPX4 活性。FINO2 是一种稳定的氧化剂，将铁氧化为氧化亚铁并在不同的 pH 值下保持稳定。FINO2 引起广泛的脂质过氧化。 |
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Gaschler, M.M., Andia, A.A., Liu, H., et al.FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidationNat. Chem. Biol.14(5),507-515(2018)
Abrams, R.P., Carroll, W.L., and Woerpel, K.A.Five-membered ring peroxide selectively initiates ferroptosis in cancer cellsACS Chem. Biol.11(5),1305-1312(2016)
