Famitinib
Cat. No.:YN270796
产品名称: | Famitinib |
CAS No.: | 1044040-56-3 |
Chemical Name: | |
Synonyms: | 法米替尼; SHR1020 |
分子量: | 暂无 |
分子式: | 暂无 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Famitinib (SHR1020) 是一种有效的,具有口服活性的多靶点激酶抑制剂,抑制c-kit,VEGFR-2和PDGFRβ的活性,IC50值分别为 2.3 nM、4.7 nM 和 6.6 nM。Famitinib具有抗肿瘤活性。且诱导细胞凋亡 (apoptosis)。 |
IC50和靶点: | [{name:"VEGFR-2:4.2 nM (IC50)"},{name: "PDGFRβ:6.6 nM (IC50)"},{name: "c-kit:2.3 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |