S65487
Cat. No.：YN270800
CAS No. ：1644600-79-2
| 产品名称: | S65487 |
| CAS No.: | 1644600-79-2 |
| Chemical Name: | |
| Synonyms: | VOB560 |
| 分子量: | 717.26 |
| 分子式: | C41H41ClN6O4 |
| SMILES: | O=C(C1=C(C)N(C)C(C2=C(C=CC(Cl)=C2)C(N3[C@@H](CC4=CC=CC=C4C3)CN5CCOCC5)=O)=C1)N(C6=CC=C(C=C6)O)C7=C(C)N(C)C(C#N)=C7 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | S65487 (VOB560) 是一种有效的选择性BCL-2抑制剂，是 S55746 的前体。S65487 对BCL-2突变也有活性，例如 G101V 和 D103Y。S65487 对MCL-1，BFL-1 和BCL-XL的亲和力较差。S65487 诱导细胞凋亡 (apoptosis) 并具有抗癌活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
