Enpp/Carbonic anhydrase-IN-1
Cat. No.：YN270817
CAS No. ：2883495-35-8
| 产品名称: | Enpp/Carbonic anhydrase-IN-1 |
| CAS No.: | 2883495-35-8 |
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| 分子量: | 411.52 |
| 分子式: | C23H25NO4S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Enpp/Carbonic anhydrase-IN-1 (compound 1e) 是一种有效的Enpp和carbonic anhydrase抑制剂，对 NPP1、NPP2、NPP3、CA-II、CA-IX 的IC50值分别 1.36、1.35、3.00、0.88、1.02 μM。Enpp/Carbonic anhydrase-IN-1 对癌细胞具有抗增殖活性，对正常细胞具有低细胞毒性。Enpp/Carbonic anhydrase-IN-1 诱导细胞凋亡 (Apoptosis)。 |
| IC50和靶点: | [{name:"CA Ⅱ:0.88 μM (IC50)"},{name: "CA Ⅸ:1.02 μM (IC50)"},{name: "NPP1:1.36 μM (IC50)"},{name: "NPP2:1.35 μM (IC50)"},{name: "NPP3:3.00 μM (IC50)"}] |
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