YZ129
Cat. No.:YN270821
CAS No. :1643120-60-8
产品名称: | YZ129 |
CAS No.: | 1643120-60-8 |
Chemical Name: | |
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分子量: | 300.317 |
分子式: | C19H12N2O2 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | YZ129 是 HSP90-磷酸酶-NFAT 通路的抑制剂,可抗胶质母细胞瘤,直接与热休克蛋白 (HSP90)结合,对NFAT核易位的IC50值为820 nM。YZ129 在 G2/M 期诱导GBM细胞周期阻滞,促进细胞凋亡,抑制肿瘤细胞增值和迁移。 |
IC50和靶点: | |
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Clinical Trial: | |
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