GZD856 formic
Cat. No.:YN270832
CAS No. :2804039-78-7
产品名称: | GZD856 formic |
CAS No.: | 2804039-78-7 |
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分子量: | 暂无 |
分子式: | 暂无 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GZD856 formic 是一种有效的和具有口服活性的PDGFRα/β抑制剂,IC50值分别为 68.6 和 136.6 nM。GZD856 formic 也是Bcr-AblT315I的抑制剂,对天然Bcr-Abl和 T315I 突变型的IC50值分别为 19.9 和 15.4 nM。GZD856 formic 具有抗肿瘤活性。 |
IC50和靶点: | [{name:"PDGFRα:68.6 nM (IC50)"},{name: "PDGFRβ:136.6 nM (IC50)"},{name: "Bcr-AblT315I:15.4 nM (IC50)"},{name: "Bcr-Abl:19.9 nM (IC50)"}] |
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