Aloperine
Cat. No.：YN250484
| 产品名称: | Aloperine |
| CAS No.: | 56293-29-9 |
| Chemical Name: | 1,3,4,6R,6aR,7,8,9,10,12,13R,13aS-dodecahydro-6,13-methano-2H-dipyrido[1,2-a:3',2'-e]azocine |
| Synonyms: | 苦豆碱 |
| 分子量: | 232.36 |
| 分子式: | C₁₅H₂₄N₂ |
| SMILES: | [H][C@]1(C2)[C@](CCCC3)([H])N3C[C@]2([H])[C@@]4([H])C(CCCN4)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aloperine 是一种在苦参类 (例如苦豆子Sophora alopecuroides L) 植物中生物碱，其具有抗癌，抗炎和抗病毒特性。_x000D_Aloperine 被广泛用于研究过敏性接触性皮炎湿疹和其他皮肤炎症。_x000D_Aloperine 诱导 HL-60 细胞中诱导凋亡apoptosis和自噬autophagy。 |
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Dang, Z., Zhu, L., Lai, W., et al.Aloperine and its derivatives as a new class of HIV-1 entry inhibitorsACS Med. Chem. Lett.7(3),240-244(2016)
Lin, Z., Huang, C.-F., Liu, X.-S., et al.In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens AitBasic Clin. Pharmacol. Toxicol.108(5),304-309(2011)
Wu, F., Hao, Y., Yang, J., et al.Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in ratsBiomed Pharmacother.89,632-641(2017)
Yuan, X.Y., Liu, W., Zhang, P., et al.Effects and mechanisms of aloperine on 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c miceEur. J. Pharmacol.629(1-3),147-152(2010)
