Ravuconazole
Cat. No.：YN250584
CAS No. ：182760-06-1
| 产品名称: | Ravuconazole |
| CAS No.: | 182760-06-1 |
| Chemical Name: | 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]-benzonitrile |
| Synonyms: | 雷夫康唑; BMS-207147; ER-30346 |
| 分子量: | 437.47 |
| 分子式: | C₂₂H₁₇F₂N₅OS |
| SMILES: | FC1=CC(F)=CC=C1[C@](CN2C=NC=N2)(O)[C@@H](C)C3=NC(C4=CC=C(C#N)C=C4)=CS3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ravuconazole (BMS-207147;ER-30346) 是一种口服的三唑抗真菌药物，能够有效广谱的抑制真菌。 |
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Hata, K., Kimura, J., Miki, H., et al.In vitro and in vivo antifungal activities of ER-30346, a novel oral triazole with a broad antifungal spectrumAntimicrob. Agents Chemother.40(10),2237-2242(1996)
Hata, K., Kimura, J., Miki, H., et al.Efficacy of ER-30346, a novel oral triazole antifungal agent, in experimental models of aspergillosis, candidiasis, and cryptococcosisAntimicrob. Agents Chemother.40(10),2243-2247(1996)
Carillo-Muñoz, A.J., Giusiano, G., Ezkurra, P.A., et al.Antifungal agents: mode of action in yeast cellsRev.Esp.Quimioter.19(2),130-139(2006)
Urbina, J.A., Payares, G., Sanoja, C., et al.In vitro and in vivo activities of ravuconazole on Trypanosoma cruzi, the causative agent of Chagas diseaseInt.J.Antimicrob.Agents21(1),27-38(2003)
Lepsheva, G.I.Design or screening of drugs for the treatment of Chagas disease: What shows the most promise?Expert Opin.Drug Discov.8(12),1479-1489(2013)
