Efinaconazole
Cat. No.：YN250649
CAS No. ：164650-44-6
| 产品名称: | Efinaconazole |
| CAS No.: | 164650-44-6 |
| Chemical Name: | αR-(2,4-difluorophenyl)-βR-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol |
| Synonyms: | 艾氟康唑; KP-103 |
| 分子量: | 348.39 |
| 分子式: | C₁₈H₂₂F₂N₄O |
| SMILES: | C[C@@H](N1CCC(CC1)=C)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Efinaconazole (KP-103) 是一种三唑类抗真菌剂，以 MIC 值分别为 0.0039 μg/mL 和 0.00098 μg/mL 抑制T. mentagrophytesSM-110和C. albicansATCC 10231菌株。Efinaconazole 对真菌病原体 (包括皮肤癣菌，念珠菌和马拉色菌属) 具有有效的体外活性。 |
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Jo Siu, W.J., Tatsumi, Y., Senda, H., et al.Comparison of in vitro antifungal activities of efinaconazole and currently available antifungal agents against a variety of pathogenic fungi associated with onychomycosisAntimicrob. Agents Chemother.57(4),1610-1616(2013)
Tatsumi, Y., Nagashima, M., Shibanushi, T., et al.Mechanism of action of efinaconazole, a novel triazole antifungal agentAntimicrob. Agents Chemother.57(5),2405-2409(2013)
