Pneumocandin B0
Cat. No.：YN250755
CAS No. ：135575-42-7
| 产品名称: | Pneumocandin B0 |
| CAS No.: | 135575-42-7 |
| Chemical Name: | (3S)-(4R,5R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4,5-dihydroxy-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-glutaminyl-3-hydroxy-(6→1)-lactam |
| Synonyms: | 纽莫康定B0; L-688786 |
| 分子量: | 1065.21 |
| 分子式: | C₅₀H₈₀N₈O₁₇ |
| SMILES: | O=C([C@](NC(C(NC([C@@](C[C@@H](O)C1)([H])N1C2=O)=O)[C@H](O)[C@H](C3=CC=C(O)C=C3)O)=O)([H])[C@H](O)CC(N)=O)N4[C@@](C(N[C@@H]([C@@H](C[C@@H](C(NC2[C@H](O)C)=O)NC(CCCCCCCC[C@@H](C)C[C@@H](C)CC)=O)O)O)=O)([H])[C@@H](O)CC4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pneumocandin B0(L-688786)是Cancidas的合成中间体。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Kurtz, M.B., Douglas, C., Marrinan, J., et al.Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesisAntimicrob. Agents Chemother.38(12),2750-2757(1994)
Chen, L., Yue, Q., Li, Y., et al.Engineering of Glarea lozoyensis for exclusive production of the pneumocandin B0 precursor of the antifungal drug caspofungin acetateAppl. Environ. Microbiol.81(5),1550-1558(2015)
