Tioconazole
Cat. No.：YN250997
| 产品名称: | Tioconazole |
| CAS No.: | 65899-73-2 |
| Chemical Name: | 1-[2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole |
| Synonyms: | 噻康唑; UK-20349 |
| 分子量: | 387.71 |
| 分子式: | C₁₆H₁₃Cl₃N₂OS |
| SMILES: | ClC1=CC=C(C(OCC2=C(Cl)SC=C2)CN3C=CN=C3)C(Cl)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tioconazole (UK-20349) 是一种广谱性的抗真菌咪唑衍生物。Tioconazole 抑制几种皮肤真菌和几种酵母菌的 MIC50分别小于 3.12 mg/L 和 9 mg/L。 |
| IC50和靶点: | |
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Fromtling, R.A.Overview of medically important antifungal azole derivativesClin. Microbiol. Rev.1(2),187-217(1988)
Jevons, S., Gymer, G.E., Brammer, K.W., et al.Antifungal activity of tioconazole (UK-20,349), a new imidazole derivativeAntimicrob. Agents Chemother.15(4),597-602(1979)
Marriott, M.S.Inhibition of sterol biosynthesis in Candida albicans by imidazole-containing antifungalsJ. Gen. Microbiol.117(1),253-255(1980)
Marriott, M.S., Brammer, K.W., Faccini, J., et al.Tioconazole, a new broad-spectrum antifungal agent: Preclinical studies related to vaginal candidiasisGynakol. Rundsch23(Suppl 1),1-11(1983)
