Tolnaftate
Cat. No.:YN251023
产品名称: | Tolnaftate |
CAS No.: | 2398-96-1 |
Chemical Name: | N-methyl-N-(3-methylphenyl)-carbamothioic acid, O-2-naphthalenyl ester |
Synonyms: | 托萘酯; NP-27 |
分子量: | 307.41 |
分子式: | C₁₉H₁₇NOS |
SMILES: | S=C(OC1=CC=C2C=CC=CC2=C1)N(C)C3=CC=CC(C)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tolnaftate (NP-27) 是合成的硫代氨基甲酸酯类抗真菌化合物。 |
IC50和靶点: | |
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Ryder, N.S., Frank, I., and Dupont, M.C.Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclateAntimicrob. Agents Chemother.29(5),858-860(1986)
Petranyi, G., Meingassner, J.G., and Mieth, H.Antifungal activity of the allylamine derivative terbinafine in vitroAntimicrob. Agents Chemother.31(9),1365-1368(1987)
Waitz, J.A., Moss, E.L., and Weinstein, M.J.Chemotherapeutic evaluation of clotrimazole [Bay b 5097, 1 (o-chloro-α-α-diphenylbenzyl) imidazole]Appl. Microbiol.22(5),891-898(1971)
Khan, S.N., Maggon, K.K., and Venkitasubramanian, T.A.Inhibition of aflatoxin biosynthesis by tolnaftateAppl. Environ. Microbiol.36(2),270-273(1978)