Ophiobolin B
Cat. No.：YN251712
| 产品名称: | Ophiobolin B |
| CAS No.: | 5601-74-1 |
| Chemical Name: | (1R,3aS,6aR,7S,9aR,10aS)-7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-dicyclopenta[a,d]cyclooctene-4-carboxaldehyde |
| Synonyms: | 蛇孢假壳素B |
| 分子量: | 402.57 |
| 分子式: | C₂₅H₃₈O₄ |
| SMILES: | C[C@@]12C[C@@]([C@@]3([H])/C(C=O)=C\C[C@@]1([H])[C@](CC2)([C@@H](C)CC/C=C(C)\C)O)([C@](C)(O)CC3=O)[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ophiobolin B 是一种Helminthosporium oryzae的二倍半萜类化合物 (sesterterpene) 的代谢产物，抑制玉米胚芽鞘的质子挤出。Ophiobolin B 抑制壳梭孢素 (FC) 促进的质子挤出，钾的摄取和细胞增大。Ophiobolins B 对不同接合菌的抗真菌作用的 MIC 值为 25-50 μg/mL。 |
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Bladt, T.T., Dürr, C., Knudsen, P.B., et al.Bio-activity and dereplication-based discovery of ophiobolins and other fungal secondary metabolites targeting leukemia cellsMolecules18(12),14629-14650(2013)
Krizsán, K., Bencsik, O., Nyilasi, I., et al.Effect of the sesterterpene-type metabolites, ophiobolins A and B, on zygomycetes fungiFEMS Microbiol Lett.313(2),135-140(2010)
