(-)-Bicuculline methochloride
Cat. No.：YN360049
CAS No. ：53552-05-9
| 产品名称: | (-)-Bicuculline methochloride |
| CAS No.: | 53552-05-9 |
| Chemical Name: | (5R)-5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium, monochloride |
| Synonyms: | l-Bicuculline methochloride |
| 分子量: | 417.84 |
| 分子式: | C₂₁H₂₀ClNO₆ |
| SMILES: | C[N+]1(C)[C@@H]([C@H]2OC(C3=C4OCOC4=CC=C32)=O)C5=C(C=C6C(OCO6)=C5)CC1.[Cl-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (-)-Bicuculline methochloride (l-Bicuculline methochloride) 是一种有效的GABAA受体拮抗剂。(-)-Bicuculline methochloride 在神经元中阻断 Ca2+激活的 K+通道介导的后超极化 (AHPs)。 |
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Collins, J.F., and Hill, R.G.(+) and (-)-bicuculline methochloride as optical isomers of a GABA antagonistNature249(460),845-847(1974)
Enna, S.J., Collins, J.F., and Snyder, S.H.Stereospecificity and structure-activity requirements of GABA receptor binding in rat brainBrain Res.124(1),185-190(1977)
