alpha-Asarone
Cat. No.：YN360940
| 产品名称: | alpha-Asarone |
| CAS No.: | 2883-98-9 |
| Chemical Name: | 1,2,4-trimethoxy-5-(1E)-1-propen-1-yl-benzene |
| Synonyms: | α-Asarone; trans-Asarone |
| 分子量: | 208.25 |
| 分子式: | C₁₂H₁₆O₃ |
| SMILES: | C/C=C/C1=C(OC)C=C(OC)C(OC)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | alpha-Asarone (α-Asarone) 是菖蒲属中主要的活性物质，具有抗抑等功效。 |
| IC50和靶点: | |
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Limón, I.D., Mendieta, L., Díaz, A., et al.Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-β(25-35)Neurosci. Lett.453(2),98-103(2009)
Sandeep, D., and Nair, C.K.Radioprotection by α-asarone: Prevention of genotoxicity and hematopoietic injury in mammalian organismMutat. Res.722(1),62-68(2011)
Zuo, H.L., Yang, F.Q., Zhang, X.M., et al.Separation of cis- and trans-Asarone from Acorus tatarinowii by preparative gas chromatographyJ. Anal. Methods Chem.,402081(2012)
Rodríguez-Páez, L., Juárez-Sanchez, M., Antúnez-Solís, J., et al.α-Asarone inhibits HMG-CoA reductase, lowers serum LDL-cholesterol levels and reduces biliary CSI in hypercholesterolemic ratsPhytomedicine10(5),397-404(2003)
Antunez-Solis, J., Hernández-Derramadero, F., Aquino-Vega, M., et al.2,4,5-trimethoxycinnamic acid: The major metabolite of α-asarone, retains most of the pharmacological properties of α-asaroneJ. Enzyme Inhib. Med. Chem.24(3),903-909(2009)
Pandit, S., Mukherjee, P.K., Ponnusankar, S., et al.Metabolism mediated interaction of α-asarone and Acorus calamus with CYP3A4 and CYP2D6Fitoterapia82(3),369-374(2011)
