(+)-Borneol
Cat. No.:YN360946
CAS No. :464-43-7
产品名称: | (+)-Borneol |
CAS No.: | 464-43-7 |
Chemical Name: | (1R,2S,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol |
Synonyms: | d-Borneol |
分子量: | 154.25 |
分子式: | C₁₀H₁₈O |
SMILES: | O[C@@H]1[C@](C2(C)C)(C)CC[C@]2([H])C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (+)-Borneol (d-Borneol) 是用于中药镇痛和麻醉的天然双环单萜,增强GABA受体活性的EC50值为248 μM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Granger, R.E., Campbell, E.L., and Johnston, G.A.R.(+)- And (–)-borneol: Efficacious positive modulators of GABA action at human recombinant α1β2γ2L GABAA receptorsBiochem. Pharmacol.69(7),1101-1111(2005)
Jiang, J., Shen, Y.Y., Li, J., et al.(+)-Borneol alleviates mechanical hyperalgesia in models of chronic inflammatory and neuropathic pain in miceEur. J. Pharmacol.757,53-58(2015)
Hur, J., Pak, S.C., Koo, B.S., et al.Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cellsPharm. Biol.51(1),30-35(2013)
Tabanca, N., Kirimer, N., Demirci, B., et al.Composition and antimicrobial activity of the essential oils of Micromeria cristata subsp. phrygia and the enantiomeric distribution of borneolJ. Agric. Food Chem.49(9),4300-4303(2001)