(-)-Borneol
Cat. No.:YN360947
CAS No. :464-45-9
产品名称: | (-)-Borneol |
CAS No.: | 464-45-9 |
Chemical Name: | (1S,2R,4S)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol |
Synonyms: | L-Borneol |
分子量: | 154.25 |
分子式: | C₁₀H₁₈O |
SMILES: | C[C@@]1(C2(C)C)CC[C@H]2C[C@H]1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (-)-Borneol对GABA受体具有高度有效的正调节作用,EC50值为237 μM。 |
IC50和靶点: | |
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Granger, R.E., Campbell, E.L., and Johnston, G.A.R.(+)- And (–)-borneol: Efficacious positive modulators of GABA action at human recombinant α1β2γ2L GABAA receptorsBiochem. Pharmacol.69(7),1101-1111(2005)
Power, F.B., and Lees, F.H.The constituents of the essential oil of Asarum canadenseJ. Chem. Soc., Trans.81,59-73(1902)
Quintans, -.J., L.J., Guimarães, A.G., Araújo, B.E.S., et al.Carvacrol, (−)-borneol and citral reduce convulsant activity in rodentsJ. Biotechnol.9(39),6566-6572(2010)
Yin, Y., Cao, L., Ge, H., et al.L-Borneol induces transient opening of the blood-brain barrier and enhances the therapeutic effect of cisplatinNeuroreport28(9),506-513(2017)