TC-G-1008
Cat. No.：YN320223
CAS No. ：1621175-65-2
| 产品名称: | TC-G-1008 |
| CAS No.: | 1621175-65-2 |
| Chemical Name: | N-[3-chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]-methanesulfonamide |
| Synonyms: | GPR39-C3 |
| 分子量: | 418.90 |
| 分子式: | C₁₈H₁₉ClN₆O₂S |
| SMILES: | CS(=O)(NC1=CC=C(CNC2=NC(NC)=NC(C3=NC=CC=C3)=C2)C(Cl)=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TC-G-1008 (GPR39-C3) 是有效的，有口服活性的GPR39激动剂，对大鼠和人类受体的EC50值分别为0.4 和 0.8 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Peukert, S., Hughes, R., Nunez, J., et al.Discovery of 2-pyridylpyrimidines as the first orally bioavailable GPR39 agonistsACS Med. Chem. Lett.5(10),1114-1118(2014)
