Capromorelin Tartrate
Cat. No.：YN320949
CAS No. ：193273-69-7
| 产品名称: | Capromorelin Tartrate |
| CAS No.: | 193273-69-7 |
| Chemical Name: | 2-amino-N-[(1R)-2-[(3aR)-2,3,3a,4,6,7-hexahydro-2-methyl-3-oxo-3a-(phenylmethyl)-5H-pyrazolo[4,3-c]pyridin-5-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-propanamide, (2R,3R)-2,3-dihydroxybutanedioate |
| Synonyms: | CP 424391-18 |
| 分子量: | 655.70 |
| 分子式: | C₃₂H₄₁N₅O₁₀ |
| SMILES: | O=C([C@@H]([C@@H](O)C(O)=O)O)O.CC(C)(N)C(N[C@H](COCC1=CC=CC=C1)C(N(C[C@]23CC4=CC=CC=C4)CCC2=NN(C)C3=O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Capromorelin Tartrate 是一种可口服的，有效的growth hormone secretagogue receptor (GHSR)激动剂，对hGHS-R1a的Ki值为 7 nM。 |
| IC50和靶点: | |
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Pan, L.C., Carpino, P.A., Lefker, B.A., et al.Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine growth hormone secretagogueEndocrine14(1),121-132(2001)
Rhodes, L., Zollers, B., Wofford, J.A., et al.Capromorelin: A ghrelin receptor agonist and novel therapy for stimulation of appetite in dogsVet. Med. Sci.4(1),3-16(2017)
MacAndrew, J.T., Ellery, S.S., Parry, M.A., et al.Efficacy of a growth hormone-releasing peptide mimetic in cardiac ischemia/reperfusion injuryEur. J. Pharmacol.423(2-3),195-202(2001)
