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Ibutamoren Mesylate

Cat. No.:YN321286

  • CAS No. :159752-10-0

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    • 生物活性
    • 参考文献
    • 产品名称: Ibutamoren Mesylate
      CAS No.: 159752-10-0
      Chemical Name: 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-propanamide, methanesulfonate
      Synonyms:伊布莫仑甲磺酸盐; MK-677; MK-0677
      分子量:624.77
      分子式:C₂₈H₄₀N₄O₈S₂
      SMILES:CC(N)(C(N[C@@H](C(N1CCC2(CN(C3=C2C=CC=C3)S(=O)(C)=O)CC1)=O)COCC4=CC=CC=C4)=O)C.CS(=O)(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ibutamoren Mesylate (MK-677) 是一种有效的,非肽段类生长激素促分泌素受体 (GHSR) 激动剂。Ibutamoren Mesylate 是一种有效的,具有口服活性的生长激素 (GH) 促分泌素。
      IC50和靶点:
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      In Vivo:
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      Solvent & Solubility:
    • Kojima, M., Hosoda, H., Date, Y., et al.Ghrelin is a growth-hormone-releasing acylated peptide from stomachNature402(6762),656-660(1999)

      Howard, A.D., Feighner, S.D., Cully, D.F., et al.A receptor in pituitary and hypothalamus that functions in growth hormone releaseScience273(5277),974-977(1996)

      Smith, R.G., Pong, S.S., Hickey, G., et al.Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary glandRecent Prog. Horm. Res.51,261-286(1996)

      Patchett, A.A., Nargund, R.P., Tata, J.R., et al.Design and biological activities of L-163,191 (MK-0677): A potent, orally active growth hormone secretagogueProc. Natl. Acad. Sci. USA92(15),7001-7005(1995)

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