STF-31
Cat. No.：YN360661
| 产品名称: | STF-31 |
| CAS No.: | 724741-75-7 |
| Chemical Name: | 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide |
| Synonyms: | STF31,STF 31 |
| 分子量: | 423.53 |
| 分子式: | C₂₃H₂₅N₃O₃S |
| SMILES: | O=C(NC1=CC=CN=C1)C2=CC=C(CNS(=O)(C3=CC=C(C(C)(C)C)C=C3)=O)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | STF-31 是一种葡萄糖转运蛋白 1(GLUT1) 的选择性抑制剂，IC50为 1 μM。 |
| IC50和靶点: | [{name:"GLUT1:1 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chan, D.A., Sutphin, P.D., Nguyen, P., et al.Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethalitySci. Transl. Med.3(94),1-9(2011)
Adams, D.J., Ito, D., Rees, M.G., et al.NAMPT is the cellular target of STF-31-like small-molecule probesACS Chem. Biol.9(10),2247-2254(2014)
Garten, A., Petzold, S., Körner, A., et al.Nampt: Linking NAD biology, metabolism, and cancerTrends Endocrinol. Metab.20(3),130-138(2009)
Boheler, K.R., Bhattacharya, S., Kropp, E.M., et al.A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targetsStem Cell Reports3,185-203(2014)
