Sennidin A
Cat. No.：YN361012
| 产品名称: | Sennidin A |
| CAS No.: | 641-12-3 |
| Chemical Name: | (9R,9′R)-rel-(+)-9,9′,10,10′-tetrahydro-4,4′,5,5′-tetrahydroxy-10,10′-dioxo-[9,9′-bianthracene]-2,2′-dicarboxylic acid |
| Synonyms: | |
| 分子量: | 538.46 |
| 分子式: | C₃₀H₁₈O₁₀ |
| SMILES: | O=C1C2=C(O)C=C(C(O)=O)C=C2[C@@]([C@@]3([H])C4=CC(C(O)=O)=CC(O)=C4C(C5=C(O)C=CC=C35)=O)([H])C6=CC=CC(O)=C16 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sennidin A 可从Cassia angustifolia分离得到，能够抑制HCV NS3 解旋酶，其IC50值为0.8 μM。Sennidin A诱导Akt和葡萄糖转运蛋白4 (GLUT4) 的磷酸化。Sennidin A刺激葡萄糖掺入。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Hattori, M., Kim, G., Motoike, S., et al.Metabolism of sennosides by intestinal floraChem. Pharm. Bull. (Tokyo)30(4),1338-1346(1982)
Metzger, W., and Reif, K.Determination of 1,8-dihydroxyanthranoids in sennaJ. Chromatogr. A740,133-138(1996)
Fairbairn, J.W., and Moss, M.J.The relative purgative activities of 1,8-dihydroxyanthracene derivativesJ. Pharm. Pharmacol.22(8),584-593(1970)
