Cetrorelix Acetate
Cat. No.：YN321781
CAS No. ：145672-81-7
| 产品名称: | Cetrorelix Acetate |
| CAS No.: | 145672-81-7 |
| Chemical Name: | N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide, acetate |
| Synonyms: | 醋酸西曲瑞克; SB-75 acetate |
| 分子量: | 1491.09 |
| 分子式: | C₇₂H₉₆ClN₁₇O₁₆ |
| SMILES: | CC(O)=O.O=C(N(CCC1)[C@@H]1C(N[C@H](C)C(N)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](CCCNC(N)=O)NC([C@@H](NC([C@H](CO)NC([C@H](NC([C@H](NC([C@H](NC(C)=O)CC2=CC3=CC=CC=C3C=C2)=O)CC4=CC=C(Cl)C=C4)=O)CC5=CN=CC=C5)=O)=O)CC6=CC=C(O)C=C6)=O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cetrorelix Acetate (SB-75 acetate) 是GnRH受体的强效拮抗剂，其IC50值为 1.21 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Beckers, T., Reiländer, H., and Hilgard, P.Characterization of gonadotropin-releasing hormone analogs based on a sensitive cellular luciferase reporter gene assayAnal. Biochem.251(1),17-23(1997)
Yano, T., Pinski, J., Halmos, G., et al.Inhibition of growth of OV-1063 human epithelial ovarian cancer xenografts in nude mice by treatment with luteinizing hormone-releasing hormone antagonist SB-75Proc. Natl. Acad. Sci. USA91(15),7090-7094(1994)
Meirow, D., Assad, G., Dor, J., et al.The GnRH antagonist cetrorelix reduces cyclophosphamide-induced ovarian follicular destruction in miceHum. Reprod.19(6),1294-1299(2004)
