BAR502
Cat. No.：YN320122
CAS No. ：1612191-86-2
| 产品名称: | BAR502 |
| CAS No.: | 1612191-86-2 |
| Chemical Name: | (3α,5β,6α,7α)-6-ethyl-24-norcholane-3,7,23-triol |
| Synonyms: | BAR 502,BAR-502,BAR502 |
| 分子量: | 392.62 |
| 分子式: | C₂₅H₄₄O₃ |
| SMILES: | C[C@H](CCO)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BAR502是FXR和GPBAR1的双重激动剂，IC50值分别为2 μM 和0.4 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
D'Amore, C., Di Leva, F.S., Sepe, V., et al.Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptorsJ. Med. Chem.57(3),937-954(2014)
