TGR5 Receptor Agonist
Cat. No.：YN320837
CAS No. ：1197300-24-5
| 产品名称: | TGR5 Receptor Agonist |
| CAS No.: | 1197300-24-5 |
| Chemical Name: | 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide |
| Synonyms: | CCDC |
| 分子量: | 361.22 |
| 分子式: | C₁₈H₁₄Cl₂N₂O₂ |
| SMILES: | ClC1=CC=CC=C1C2=NOC(C)=C2C(N(C)C3=CC=C(Cl)C=C3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TGR5 Receptor Agonist (CCDC) 是TGR5(GPCR19)激动剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Evans, K.A., Budzik, B.W., Ross, S.A., et al.Discovery of 3-aryl-4-isoxazolecarboxamides as TGR5 receptor agonistsJ. Med. Chem.52(24),7962-7965(2009)
Jensen, D.D., Godfrey, C.B., Niklas, C., et al.The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane raftsJ. Biol. Chem.288(32),22942-22960(2013)
