AR 231453
Cat. No.：YN321005
| 产品名称: | AR 231453 |
| CAS No.: | 733750-99-7 |
| Chemical Name: | N-[2-fluoro-4-(methylsulfonyl)phenyl]-6-[4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-5-nitro-4-pyrimidinamine |
| Synonyms: | N-(2-Fluoro-4-(methylsulfonyl)phenyl)-6-(4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-5-nitropyrimidin-4-amine;AR 231453;N-(2-FLUORO-4-METHANESULFONYLPHENYL)-(6-[4-(3-ISOPROPYL-[1,2,4]OXADIAZOL-5-YL)-PIPERIDIN-1-YL]-5-NITRO-PYRIMIDIN-4-YL)A...;(2-f |
| 分子量: | 505.52 |
| 分子式: | C₂₁H₂₄FN₇O₅S |
| SMILES: | CC(C)C1=NOC(C2CCN(C3=NC=NC(NC4=CC=C(S(=O)(C)=O)C=C4F)=C3[N+]([O-])=O)CC2)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AR 231453 是有效的、特异性的、具有口服活性的GPR119激动剂。AR 231453 可刺激细胞增殖，改善胰岛 β 细胞的功能。 |
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Chu, Z.L., Jones, R.M., He, H., et al.A role for ß-cell-expressed GPR119 in glycemic control by enhancing glucose-dependent insulin releaseEndocrinology148(6),2601-2609(2007)
