AM-4668
Cat. No.:YN320615
产品名称: | AM-4668 |
CAS No.: | 1011531-27-3 |
Chemical Name: | (βS)-β-[4-[[4-Methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl)-3-isoxazolepropanoic Acid; (S)-3-(Isoxazol-3-yl)-3-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]thiazol-5-yl]methoxy]phenyl]propanoic Acid |
Synonyms: | |
分子量: | 488.48 |
分子式: | C₂₄H₁₉F₃N₂O₄S |
SMILES: | OC(C[C@H](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AM-4668 是一种GPR40激动剂,用于2 型糖尿病研究。在 A9 细胞中和 CHO 细胞,激活 GPR40 的EC50分别为 3.6 nM 和 36 nM。 |
IC50和靶点: | |
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Clinical Trial: | |
Solvent & Solubility: |
Liu, J.
et al.: ACS Med. Chem. Lett., 5, 517 (2014)