GW-1100
Cat. No.：YN321283
| 产品名称: | GW-1100 |
| CAS No.: | 306974-70-9 |
| Chemical Name: | 4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-benzoic acid, ethyl ester |
| Synonyms: | GW1100;GW1100 |
| 分子量: | 520.58 |
| 分子式: | C₂₇H₂₅FN₄O₄S |
| SMILES: | O=C1C(CC2=CN=C(N=C2)OCC)=CN(C(SCC3=CC=C(C=C3)F)=N1)C4=CC=C(C(OCC)=O)C=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GW-1100是选择性的GPR40拮抗剂，pIC50为6.9。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Briscoe, C.P., Peat, A.J., McKeown, S.C., et al.Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: Identification of agonist and antagonist small moleculesBr. J. Pharmacol.148(5),619-628(2006)
