6-OAU
Cat. No.:YN320640
产品名称: | 6-OAU |
CAS No.: | 83797-69-7 |
Chemical Name: | 6-(octylamino)-2,4(1H,3H)-pyrimidinedione |
Synonyms: | GTPL5846 |
分子量: | 239.31 |
分子式: | C₁₂H₂₁N₃O₂ |
SMILES: | O=C1NC(C=C(NCCCCCCCC)N1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 6-OAU(GTPL5846; 6-n-octylaminouracil)是GPR84激动剂,在PI assay中EC50值为105nM。 |
IC50和靶点: | |
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Davenport, A.P., Alexander, S.P.H., Sharman, J.L., et al.International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: Recommendations for new pairings with cognate ligandsPharmacol. Rev.65(3),967-986(2013)
Suzuki, M., Takaishi, S., Nagasaki, M., et al.Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptorJ. Biol. Chem.288(15),10684-10691(2013)