TWS119
Cat. No.:YN420053
产品名称: | TWS119 |
CAS No.: | 601514-19-6 |
Chemical Name: | 3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol |
Synonyms: | TWS-119, TWS 119 |
分子量: | 318.33 |
分子式: | C₁₈H₁₄N₄O₂ |
SMILES: | OC1=CC=CC(OC2=C3C(NC(C4=CC=CC(N)=C4)=C3)=NC=N2)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TWS119 是一种GSK-3β特异性抑制剂,IC50值为 30 nM,同时可激活 wnt/β-catenin 信号通路。 |
IC50和靶点: | [{name:"GSK-3β:30 nM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Ding, S., Wu, T.Y.H., Brinker, A., et al.Synthetic small molecules that control stem cell fateProc. Natl. Acad. Sci. USA100(13),7632-7637(2003)