BIP-135
Cat. No.：YN420074
CAS No. ：941575-71-9
规格
价格(RMB)
库存
| 产品名称: | BIP-135 |
| CAS No.: | 941575-71-9 |
| Chemical Name: | 3-(Benzofuran-3-yl)-4-(5-bromo-1-methyl-1H-indol-3-yl)pyrrole-2,5-dione; BIP 135; |
| Synonyms: | |
| 分子量: | 421.24 |
| 分子式: | C₂₁H₁₃BrN₂O₃ |
| SMILES: | O=C(C(C1=COC2=CC=CC=C12)=C3C4=CN(C)C5=C4C=C(Br)C=C5)NC3=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BIP-135 是一个高效、选择性的，ATP 竞争性的GSK-3抑制剂，对 GSK-3α 和 GSK-3β 作用的IC50值分别为 16 nM 和 21 nM。BIP 135 具有神经保护作用。 |
| IC50和靶点: | [{name:"GSK-3α:16 nM (IC50)"},{name: "GSK-3β:21 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chen, P.C. et al.: ACS Chem. Neurosci., 3, 5 (2012)
