5-Iodo-indirubin-3'-monoxime
Cat. No.:YN420081
产品名称: | 5-Iodo-indirubin-3'-monoxime |
CAS No.: | 331467-03-9 |
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Synonyms: | |
分子量: | 403.17 |
分子式: | C₁₆H₁₀IN₃O₂ |
SMILES: | O/N=C(C1=CC=CC=C1N2)/C2=C3C(NC4=C/3C=C(I)C=C4)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 5-Iodo-indirubin-3'-monoxime 是一种有效的GSK-3β,CDK5/P25和CDK1/cyclin B抑制剂,与 ATP 竞争性地结合酶的催化位点,IC50值分别为 9,20 和 25 nM。 |
IC50和靶点: | [{name:"GSK-3β:9 nM (IC50)"},{name: "Cdk5/p25:20 nM (IC50)"},{name: "Cdk1/cyclin B:25 nM (IC50)"}] |
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