Indirubin-5-sulfonate
Cat. No.：YN420083
CAS No. ：244021-67-8
规格
价格(RMB)
库存
| 产品名称: | Indirubin-5-sulfonate |
| CAS No.: | 244021-67-8 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 342.33 |
| 分子式: | C₁₆H₁₀N₂O₅S |
| SMILES: | O=S(C1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C/3=O)=O)C=C1)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Indirubin-5-sulfonate 是周期蛋白依赖性激酶(CDK)的抑制剂，对CDK1/cyclin B、CDK2/cyclin A、CDK2/cyclin E、CDK4/cyclin D1 和CDK5/p35 的IC50值分别为55 nM、35 nM、150 nM、300 nM 和 65 nM。Indirubin-5-sulfonate 同样能抑制GSK-3β的活性。 |
| IC50和靶点: | [{name:"Cdk1/cyclin B:55 nM (IC50)"},{name: "cdk2/cyclin A:35 nM (IC50)"},{name: "CDK2/cyclinE:150 nM (IC50)"},{name: "Cdk4/cyclin D1:300 nM (IC50)"},{name: "CDK5/p35:65 nM (IC50)'}, 'GSK-3β'] |
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| Clinical Trial: | |
| Solvent & Solubility: |
